Wegovy (Semaglutide) Tablets
Weight Loss
Overview
NOTE: You must complete a short assessment so we can make sure the medication for this condition is suitable for you.
Wegovy Weight Loss Tablets are a once-daily prescription treatment designed for chronic weight management. They contain the active ingredient semaglutide, a GLP-1 weight loss medicine that works by regulating appetite and controlling food intake. By helping you feel fuller faster, Wegovy tablets support reduced calorie consumption and promote sustainable eating habits.
This weight loss tablet can be highly effective when combined with lifestyle changes such as a low-calorie diet, regular physical activity, and healthy eating choices — with the same active ingredient as the Wegovy injection, now available without a needle.
How It Works
The active ingredient in Wegovy weight loss tablets is called semaglutide, a GLP-1 receptor agonist. This synthetic version of the glucagon-like peptide-1 (GLP-1) hormone is naturally released by your gut after eating and plays a crucial role in regulating blood sugar levels and controlling appetite.
Semaglutide in Wegovy mimics the effects of GLP-1 by sending signals to your brain, making you feel fuller faster and reducing appetite while effectively curbing food cravings. Additionally, it slows stomach emptying, allowing you to feel satisfied for longer periods after eating.
By acting as a hormone-based appetite suppressant, semaglutide helps regulate appetite control centres in the brain, leading to decreased calorie intake. This key mechanism makes Wegovy an effective medication for weight management, especially when paired with lifestyle changes such as a healthy diet and regular physical activity.
The Dosing
You'll take the Wegovy weight loss tablet once daily, on an empty stomach, swallowed whole with up to half a glass (120ml) of water — waiting at least 30 minutes before eating, drinking, or taking any other medicines. The routine is simple, and our friendly clinicians are always available to address any questions or concerns you might have about using this GLP-1 weight loss medication.
When starting Wegovy tablet treatment, you'll begin with a low 1.5mg starting dose. Your prescriber will gradually increase the dosage over several months until you reach your recommended maintenance dose. This slow titration process allows your body to adjust comfortably and helps minimise potential gastrointestinal side effects.
If you are switching from Injectables to tablets our team will help you inderstand what dose youshould be moving to. please complete the assessment forms and we will help get you started.
FAQ
Can I switch from the Wegovy injection to Wegovy tablets?
Yes. If you're currently using an injectable weight loss medication, you can switch to Wegovy tablets under the guidance of your prescriber, who will agree the right starting dose with you.
Can I take the injection and the tablet at the same time?
No. Do not take both injectable and oral weight loss medication at the same time.
When do I start taking the tablet after my last injection?
Start oral Wegovy on the date your next injection would have been due. This builds in a one-week washout period for the injectable medication before you begin the tablet.
Will my dose be the same as my injection dose?
No. Your dose will need to be adjusted when switching to tablets, as the strength and absorption of the tablet differ from the injection. Your prescriber will set a new starting dose rather than matching your injectable strength directly.
Will I notice a difference in how the tablet works compared to the injection?
Weight loss results may vary after switching. Some people notice changes in appetite control or their weight loss response while adjusting to the tablet — this is a normal part of the transition and not a sign the treatment isn't working.
Do I still need to watch for side effects when switching?
Yes. Monitor for side effects, especially nausea, vomiting, diarrhoea, constipation, stomach pain, indigestion or reduced appetite. Seek medical advice if you get severe or persistent abdominal pain — especially if it spreads to your back — or any visual disturbances. Stay hydrated, particularly if you experience vomiting or diarrhoea.
Do I still need to keep up healthy lifestyle changes after switching?
Yes. Continue healthy lifestyle changes including a balanced diet, reduced calorie intake, and regular physical activity — these remain just as important on the tablet as they were on the injection.
What is Wegovy?
WEGOVY (semaglutide) tablets 25 mg is an oral prescription medicine used with a reduced calorie diet and increased physical activity:
to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight.
that may help adults with obesity, or some adults with overweight who also have weight-related medical problems, to help them lose excess body weight and keep the weight off.
Wegovy contains semaglutide and should not be used with other semaglutide-containing products or other GLP-1 receptor agonist medicines.How does Wegovy work for weight loss?
Wegovy works by mimicking a hormone that targets areas of the brain involved in regulating appetite and food intake. This can help you eat less, which can lead to weight loss.
How soon can I expect to lose weight with Wegovy?
People respond to medicines differently, so there is no set time for when you can expect to see results with Wegovy. Ask your health care professional about what might be a realistic expectation for you.
What are the most common side effects of Wegovy Tablets?
The most common side effects of Wegovy tablets may include: nausea, diarrhoea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, and heartburn.
Tell your health care professional if you have any side effects that bother you.
Can I travel with my Wegovy tablets?
Yes. Wegovy tablets are stored at room temperature, so there's no need to worry about them freezing or overheating in transit the way an injection pen would. Keep them in their original packaging and check your airline's rules on carrying prescription medication.
How often is Wegovy taken?
Wegovy is taken once daily, on an empty stomach, first thing in the morning — swallowed whole with up to half a glass (120ml) of water, waiting at least 30 minutes before eating, drinking, or taking any other medicines.
Why are there different tablet strengths?
Wegovy comes in four doses: 1.5mg, 4mg, 9mg, and 25mg. Your dose is increased gradually over several months to help your body adjust.
Do I have to take Wegovy at the same time every day?
It's recommended that you take Wegovy at the same time each day, on an empty stomach, to help it absorb properly and to build it into your routine.
Can I change the time when I take Wegovy?
Yes, you can adjust the time of day you take it, as long as you keep taking it once daily on an empty stomach with the required 30-minute wait before food, drink, or other medicines.
Should I take Wegovy with a meal?
No — unlike the injection, Wegovy tablets must be taken on an empty stomach. Taking it with food can significantly reduce how much of the medicine your body absorbs.
What do I do if my Wegovy tablets look damaged or discoloured?
Wegovy tablets should look intact and consistent with the description in the patient information leaflet. If a tablet looks damaged, discoloured, or different from usual, do not take it — safely dispose of it and contact us via the contact form.
How can I dispose of unused Wegovy tablets?
Return any unused or out-of-date tablets to a pharmacy for safe disposal. Do not put them in household waste or flush them.
Does my Wegovy need to be kept in the fridge?
No. Wegovy tablets are stored at room temperature (below 30°C) and don't require refrigeration, ice packs, or cold-chain packaging at any stage — from our pharmacy to your door.
Is my Wegovy still safe to use?
Yes. Wegovy tablets are stable at room temperature, so standard packaging is all that's needed to keep your medication safe and effective in transit. We continue to dispatch your order quickly and in protective packaging so it arrives in the best possible condition.
Side Effects
As with any weight loss medication, there is a possibility of side effects when taking Wegovy weight loss tablets.
The most common side effects of Wegovy are typically mild gastrointestinal issues, including nausea, vomiting, diarrhoea, and constipation. Some patients may also experience fatigue, headaches, dizziness, or indigestion, especially during the initial dosing period.
We understand that managing side effects can be challenging while maintaining healthy lifestyle habits. Our team is here to offer ongoing support, expert advice, and encouragement to help you achieve your weight loss goals. If you experience any troublesome side effects, don't hesitate to reach out for assistance.
Because Wegovy tablets are an MHRA approved weight loss medication and relatively new to the market, they are under close safety monitoring. Please report any side effects to the Yellow Card Scheme, even if they are not listed in the patient information leaflet. Your feedback helps contribute to the ongoing safety profile of this GLP-1 weight loss medication.
While rare, serious side effects of Wegovy may include severe allergic reactions, pancreatitis, or gallstones. Seek immediate medical attention if you experience symptoms such as persistent abdominal pain, difficulty breathing, swelling, or trouble swallowing.
Compare
Treatment Comparison
| WEGOVY Injection | SAXENDA Injection | XENICAL / ORLISTAT Capsule | MOUNJARO Injection | WEGOVY Tablet | |
| Active Ingredient | Semaglutide | Liraglutide | Orlistat | Tirzepatide | Semaglutide |
| How does it work? | Helps you feel fuller and reduces food cravings | Helps you feel fuller and reduces food cravings | Reduces how much fat your body can absorb from the food you eat | Helps you feel fuller and reduces food cravings | Helps you feel fuller and reduces food cravings |
| How do I take it? | It’s self-injected | It’s self-injected | You swallow a capsule | It’s self-injected | Oral Tablet |
| When do I take it? | Once a Week | Once a Day | Up to three times a day with meals | Once a Week | Once daily |
| Is it prescription only? | Yes | Yes | Yes | Yes | Yes |
| How long do I take it for? | Obesity is treated as a chronic medical condition; medicines can be taken long-term to help you reach a healthier weight but for long lasting weight loss you’ll need to make lifestyle changes as well | Obesity is treated as a chronic medical condition; medicines can be taken long-term to help you reach a healthier weight but for long lasting weight loss you’ll need to make lifestyle changes as well | Obesity is treated as a chronic medical condition; medicines can be taken long-term to help you reach a healthier weight but for long lasting weight loss you’ll need to make lifestyle changes as well | Obesity is treated as a chronic medical condition; medicines can be taken long-term to help you reach a healthier weight but for long lasting weight loss you’ll need to make lifestyle changes as well | Obesity is treated as a chronic medical condition; medicines can be taken long-term to help you reach a healthier weight but for long lasting weight loss you’ll need to make lifestyle changes as well |
| How else can you help me? | There are plenty of non-medicinal routes you can take to reach your weight loss goals, please check the NHS site for the most up to date plans and advice | There are plenty of non-medicinal routes you can take to reach your weight loss goals, please check the NHS site for the most up to date plans and advice | There are plenty of non-medicinal routes you can take to reach your weight loss goals, please check the NHS site for the most up to date plans and advice | There are plenty of non-medicinal routes you can take to reach your weight loss goals, please check the NHS site for the most up to date plans and advice | There are plenty of non-medicinal routes you can take to reach your weight loss goals, please check the NHS site for the most up to date plans and advice |
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