How to Switch Between Mounjaro and Wegovy
Understanding the Difference
Mounjaro (tirzepatide) acts on two hormone receptors — GLP-1 and GIP — offering dual appetite and blood sugar control.
Wegovy (semaglutide) works on GLP-1 receptors only but remains highly effective for weight loss.
Because these drugs act differently, there’s no simple one-to-one dose swap. Your doctor will need to design a personalised transition plan.
How to Switch Safely
Consult Your Clinician – Discuss your reasons for switching and review your current progress.
Plan the Transition – Depending on your dose, you may need a gap or overlap period before starting Wegovy.
Start Low and Go Slow – Wegovy is usually introduced at a lower dose and gradually increased to minimise side effects.
Monitor Progress – Weight, appetite, and any side effects should be closely tracked during the first few weeks.
Review and Adjust – Your prescriber may fine-tune your dose or timing to ensure a smooth transition.
Key Considerations
Mounjaro may produce greater weight loss in some users, but Wegovy often offers better accessibility and lower cost.
Switching without guidance can lead to side effects, plateaus, or temporary weight regain.
Always make medication changes through a regulated clinic.
Treat Discreet Can Help
Our clinicians provide one-on-one guidance to help you transition safely between medications. We create personalised plans, monitor your progress, and ensure your results continue without interruption.
Switching between Mounjaro and Wegovy is entirely possible — it just needs to be done safely. Book a consultation with Treat Discreet to plan your transition with expert support.
